The science behind Sculptra®

The factors influencing changes in our skin and facial structure

Over time, multiple internal and external factors can lead to a visible decline in our skin’s appearance.8 Examples are smoking and prolonged sun exposure (external factors), a natural loss of collagen and elastin in our skin, a decrease and sliding of the fat pads, and a gradual degradation of our facial bone structure.9-12

Collagen and elastin are the key internal components for youthful skin10-14

Did you know that we lose about 1% of the collagen in our bodies per year from the age of 20?13 Sculptra® is made with the unique PLLA-SCA™ formulation, which works across all 3 skin layers.7,15,16 The treatment stimulates the production of our own collagen and elastin, with an increase in collagen type I, the most important collagen for youthful skin, by 66.5% at 3 months.6,7,17-21

Sculptra® addresses different skin needs and concerns

Over time, Sculptra® progressively restores the skin’s natural structure, addressing a range of different needs and concerns, such as loss of firmness and radiance, facial volume loss and skin sagging.18-25

A treatment tailored to your own specific needs

Over time, due to lifestyle factors (like sun exposure and smoking) as well as natural aging, we may notice a range of different changes in our skin and face.8-12 These changes can be experienced in different ways, such as:

“My skin is turning dull and I’m starting to look older.”

“My face has lost natural volume, I look tired and unhealthy.”

“My face has started to fall. I look old and saggy.”

“My lower face looks too full and I want to look slimmer.”

No matter your concern, a treatment with Sculptra® can be tailored to suit your needs. Look better and feel better with skin that feels like you again.

Natural-looking results that make people feel better about themselves

The vast majority (89%) of people who have had a Sculptra® treatment think the results look natural and that they look younger.22 They also feel better about themselves and more confident (92%). Not surprisingly, 9 out of 10 would recommend Sculptra® to a friend,26 and 85% would have a Sculptra® treatment again.22

Find a specialist

Talk with your healthcare practitioner to find out
how 
Sculptra® can help you get skin that feels like you again.

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Frequently asked questions

References

1. Sculptra. Instructions for Use EU 2021. 2. Galderma Receives FDA Approval for New SCULPTRA® Label, Offering More Options to Aesthetic Partners. Galderma. 2021. Available from: https://www.galderma.com/news/galderma-receives-fda-approvalnew-sculptra-label-offering-more-options-aesthetic-partners [Last accessed June 2024]. 3. Asius J, et al. US patent US 7,731,758 B22(010):2010. 4. Sanofi S.r.l. DEKRA EN ISO 13485:2016 Certificate. Certificate effective since: February 2023. 5. Zhang Y, et al. Regen Biomater 2021;8(5):rbab042. 
6. Widgerow A, et al. A randomized, comparative study describing the gene signatures of poly-l-lactic acid (PLLA-SCA) and calcium hydroxylapaptite (CaHA) in the treatment of nasolabial folds. Poster presented at the International Master Course on Aging Science (IMCAS) World Congress. 1–3 February 2024. 7. Hexsel D, et al. Dermatol Surg. 2020;46(8):1122–4.8. Vierkötter A, Krutmann J. Dermatoendocrinol. 2012;4(3):227–31. 9. Zhang S, Duan E. Cell Transplantation. 2018;27(5):729–38.10. Aziz J, et al. Skin Pharmacol Physiol. 2016;29(4):190–203. 11. Swift A, et al, Aesthet Surg J. 2021;41(10):1107–19. 12. Data on File (MA-54104). 13. Goldberg D, et al. Dermatol Surg. 2013;39(6):915–22. 14. Mest DR, Humble G. Dermatol. Surg. 2006;32(11):1336–45. 15. Bohnert K, et al. Plast Reconstr Surg 2019;45(5):718–24. 16. Filho CDSM, et al. Surg Cosmet Dermatol. 2013;5(4):345–50. 17. Fabi S, et al. Effectiveness and safety of correction of cheek wrinkles. Poster presented at the International Master Course on Aging Science (IMCAS) World Congress. 26–28 January 2023. Paris, France. 18. Fabi S, et al. Skin movement and volume changes with poly-L lactic acid (PLLA-SCA) injectable implant. Poster presented at the International Master Course on Aging Science (IMCAS) World Congress. 26–28 January 2023. Paris, France. 19. Data on file (MA-48331).

Always consult a healthcare professional for individualized treatment recommendations and to
discuss important
safety information and risks associated with the use of the products.